Description

4-Piperidinemethanol, 1-(Trifluoroacetyl)- (9Ci) is a high-purity, functionalized piperidine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its trifluoroacetyl-protected amine group and hydroxymethyl handle, enabling precise chemical modifications for creating complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of piperidine-based drug candidates, including potential central nervous system (CNS) agents and enzyme inhibitors.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging the piperidine scaffold for biological activity.
• Chemical Synthesis Building Block: Employed in medicinal chemistry for lead optimization and structure-activity relationship (SAR) studies due to its versatile reactive sites.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands or catalysts used in asymmetric synthesis.
• Academic and R&D Laboratories: Utilized in fundamental research exploring new synthetic methodologies and heterocyclic chemistry.
• Fine Chemical Production: Incorporated into the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	4-Piperidinemethanol, 1-(Trifluoroacetyl)- (9Ci)
CAS No.	156459-82-4
Molecular Formula	C8H12F3NO2
Molecular Weight	211.18 g/mol
Synonyms	1-(Trifluoroacetyl)-4-piperidinemethanol; 4-(Hydroxymethyl)-1-(trifluoroacetyl)piperidine; 1-(Trifluoroacetyl)-4-piperidinemethanol (9CI); 4-Piperidinemethanol, 1-(trifluoroacetyl)-; 1-Trifluoroacetyl-4-piperidinemethanol; 4-(Hydroxymethyl)-N-(trifluoroacetyl)piperidine; N-Trifluoroacetyl-4-piperidinemethanol
EINECS	Contact for details

Quality Control

Our 4-Piperidinemethanol, 1-(Trifluoroacetyl)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.