Description

1-Piperazinecarboxylicacid,3-Oxo-,2-Propenylester(9Ci) is a specialized heterocyclic building block with a reactive acrylate ester group. This compound matters for its role as a key intermediate in the synthesis of complex pharmacologically active molecules, offering a versatile handle for further chemical modification. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new drug candidates, particularly in the areas of protease inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, especially protease inhibitors and other targeted therapies.
• Chemical Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Peptidomimetic Synthesis: Serves as a core scaffold for creating peptidomimetics, which mimic the structure and function of natural peptides.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the custom production of advanced intermediates.
• Bioconjugation Chemistry: The acrylate ester moiety can be utilized in conjugation reactions for labeling or linking molecules.

Basic Information

Product Name	1-Piperazinecarboxylicacid,3-Oxo-,2-Propenylester(9Ci)
CAS No.	156440-97-0
Molecular Formula	C8H12N2O3
Molecular Weight	184.19 g/mol
Synonyms	3-Oxo-1-piperazinecarboxylic acid 2-propenyl ester; Allyl 3-oxopiperazine-1-carboxylate; 1-Allyloxycarbonyl-3-oxopiperazine; 1-(Allyloxycarbonyl)-3-oxopiperazine; 3-Oxo-1-(2-propen-1-yloxycarbonyl)piperazine; 1-Carboxy-3-oxopiperazine allyl ester; Acryloyl piperazinone derivative; Piperazine-1-carboxylic acid, 3-oxo-, 2-propenyl ester
EINECS	Contact for details

Quality Control

Our 1-Piperazinecarboxylicacid,3-Oxo-,2-Propenylester(9Ci) is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.