Description

4-(2-Iodobenzyl)Morpholine is a versatile and high-value organic building block featuring a morpholine ring linked to a 2-iodobenzyl group. This compound matters for its crucial role as a key intermediate in modern synthetic organic chemistry, enabling the construction of complex molecules through cross-coupling and other advanced reactions. Pharmaceutical, agrochemical, and advanced material research laboratories need it for developing new active ingredients and functional materials, where precise molecular architecture is paramount.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the iodine atom serves as a handle for further functionalization.
• Ligand & Catalyst Synthesis: Employed in the preparation of specialized ligands for transition metal catalysis, enhancing reaction selectivity and efficiency.
• Material Science: Serves as a building block for creating organic semiconductors, liquid crystals, and other functional polymers with tailored electronic properties.
• Cross-Coupling Reactions: Primarily utilized in Suzuki-Miyaura, Stille, and other palladium-catalyzed cross-coupling reactions to form new carbon-carbon bonds.
• Chemical Biology Probes: Acts as a scaffold for developing molecular probes and tags used in biochemical and cellular imaging studies.

Basic Information

Item	Detail
Product Name	4-(2-Iodobenzyl)Morpholine
CAS No.	156333-95-8
Molecular Formula	C11H14INO
Molecular Weight	303.14 g/mol
Synonyms	2-((Morpholin-4-yl)methyl)-1-iodobenzene; 1-Iodo-2-(morpholin-4-ylmethyl)benzene; 4-[(2-Iodophenyl)methyl]morpholine; N-(2-Iodobenzyl)morpholine; 2-Iodobenzylmorpholine; Morpholine, 4-[(2-iodophenyl)methyl]-; 156333-95-8
EINECS	Contact for details

Quality Control

Our 4-(2-Iodobenzyl)Morpholine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.