Description

4,7-Methano-4H-1,3-Dioxolo[4,5-D][1,2]Oxazine, Tetrahydro-2,2-Dimethyl-6-(Phenylmethyl)-, (3As,4S,7R,7As)- is a high-purity, stereochemically defined bicyclic oxazine derivative with a complex molecular architecture. This compound serves as a critical chiral building block and advanced intermediate in sophisticated organic synthesis, enabling the construction of molecules with precise three-dimensional structures. It is primarily required by pharmaceutical R&D and fine chemical synthesis laboratories for developing novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for complex target molecules.
• Asymmetric Synthesis: Utilized as a building block to introduce stereochemical complexity in the synthesis of natural products and bioactive compounds.
• Ligand and Catalyst Development: Serves as a precursor for novel chiral ligands or organocatalysts used in enantioselective transformations.
• Agrochemical Research: Employed in the synthesis of advanced, stereospecific pesticide and herbicide candidates.
• Material Science: Potential monomer or precursor for specialized polymers and advanced organic materials requiring specific structural motifs.
• Academic & Industrial R&D: Used in chemical research for methodology development and exploring new reaction pathways involving strained or functionalized heterocycles.

Basic Information

Product Name	4,7-Methano-4H-1,3-Dioxolo[4,5-D][1,2]Oxazine, Tetrahydro-2,2-Dimethyl-6-(Phenylmethyl)-, (3As,4S,7R,7As)-
CAS No.	155855-51-9
Molecular Formula	C16H21NO3
Molecular Weight	275.34 g/mol
Synonyms	(3aS,4S,7R,7aS)-Tetrahydro-2,2-dimethyl-6-(phenylmethyl)-4,7-methano-4H-[1,3]dioxolo[4,5-d][1,2]oxazine; 6-Benzyl-2,2-dimethyltetrahydro-4,7-methano[1,3]dioxolo[4,5-d][1,2]oxazine; Chiral Bicyclic Oxazine Derivative; (4S,7R)-6-Benzyl-2,2-dimethyltetrahydro-4,7-methano[1,3]dioxolo[4,5-d][1,2]oxazine; 155855-51-9; Benzyl-Substituted Tetrahydro Methano Dioxolo Oxazine
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Quality is verified through comprehensive analytical techniques including HPLC, GC, chiral analysis, and NMR spectroscopy. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and enantiomeric excess. We support compliance with cGMP standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.