Description

(2R,5R)-2,5-Dimethyl-Piperazine is a high-purity, stereochemically defined chiral piperazine derivative. This compound is a critical chiral building block and ligand, valued for its ability to impart stereoselectivity in complex chemical syntheses. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral, anticancer, and central nervous system (CNS) drugs.
• Asymmetric Catalysis: Serves as a precursor for chiral ligands and organocatalysts used in enantioselective synthesis, including hydrogenation and cross-coupling reactions.
• Agrochemical Synthesis: Used in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Complex Ligand Preparation: Building block for creating sophisticated polydentate ligands used in coordination chemistry and metal complexation.
• Research & Development: A valuable standard and reagent in academic and industrial R&D for exploring new synthetic methodologies and chiral separations.
• Polymer Modification: Can be incorporated into polymer chains to create materials with specific chiral or chelating properties.

Basic Information

Product Name	(2R,5R)-2,5-Dimethyl-Piperazine
CAS No.	155836-53-6
Molecular Formula	C6H14N2
Molecular Weight	114.19 g/mol
Synonyms	(2R,5R)-2,5-Dimethylpiperazine; (R,R)-2,5-Dimethylpiperazine; cis-2,5-Dimethylpiperazine; (2R,5R)-2,5-Dimethyl-piperazine; 2,5-Dimethylpiperazine, (R,R)-; (R,R)-(-)-2,5-Dimethylpiperazine; Piperazine, 2,5-dimethyl-, (2R,5R)-; (2R,5R)-(-)-2,5-Dimethylpiperazine
EINECS	Contact for details

Quality Control

Our (2R,5R)-2,5-Dimethyl-Piperazine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed specifications for identity, assay, enantiomeric excess, and impurities are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.