Description

2,5-Piperazinedione,3,6-Dimethyl-1-(2-Propenyl)-,(3S-Trans)-(9Ci) is a specialized chiral piperazinedione derivative, a key structural motif in medicinal chemistry. This compound matters as a versatile and high-purity pharmaceutical intermediate or building block for the synthesis of complex molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for creating novel active pharmaceutical ingredients (APIs) and exploring new chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the multi-step synthesis of potential drug candidates, particularly those targeting neurological or oncological pathways.
• Peptidomimetic Research: Used in the design and development of peptidomimetics, where the piperazinedione core mimics peptide bonds to enhance metabolic stability and bioavailability.
• Asymmetric Synthesis: Employed as a starting material or chiral auxiliary in asymmetric synthesis to induce stereoselectivity in the formation of new chiral centers.
• Medicinal Chemistry R&D: Utilized in high-throughput screening libraries and structure-activity relationship (SAR) studies to explore new therapeutic targets.
• Chemical Reference Standard: Acts as a high-purity analytical standard for method development and quality control in API manufacturing.
• Academic Research: Applied in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	2,5-Piperazinedione,3,6-Dimethyl-1-(2-Propenyl)-,(3S-Trans)-(9Ci)
CAS No.	155767-05-8
Molecular Formula	C9H14N2O2
Molecular Weight	182.22 g/mol
Synonyms	(3S,6S)-3,6-Dimethyl-1-(prop-2-en-1-yl)piperazine-2,5-dione; (3S-trans)-3,6-Dimethyl-1-(2-propenyl)-2,5-piperazinedione; 1-Allyl-3,6-dimethylpiperazine-2,5-dione (stereospecific); (S,S)-1-Allyl-3,6-dimethyl-2,5-diketopiperazine; DKP derivative, chiral allyl-substituted; Chiral Diketopiperazine building block; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our 2,5-Piperazinedione derivative is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our commitment to cGMP principles ensures traceability and consistency for critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.