Description

2-Chloro-Pyrido[2,3-B]Pyrazine is a high-value, heterocyclic aromatic compound featuring a fused pyridine-pyrazine ring system substituted with a reactive chlorine atom. This structure makes it a versatile and critical chemical building block for advanced synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in creating complex molecules for medicinal chemistry and agrochemical applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting kinase inhibition and other biological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive heterocyclic core.
• Material Science: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic semiconductors.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the pyridopyrazine moiety into more complex molecular architectures.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploration of new chemical spaces.

Basic Information

Product Name	2-Chloro-Pyrido[2,3-B]Pyrazine
CAS No.	155535-23-2
Molecular Formula	C7H4ClN3
Molecular Weight	165.58 g/mol
Synonyms	2-Chloropyrido[2,3-b]pyrazine; 2-Chloro-pyrido[2,3-b]pyrazine; Pyrido[2,3-b]pyrazine, 2-chloro-; 2-Chloro-4-azaindolizine; 2-Chloro-1,5-naphthyridine
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity. Our standard grade for 2-Chloro-Pyrido[2,3-B]Pyrazine typically meets a purity specification of ≥97% (by HPLC), suitable for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment. We can support custom synthesis to meet specific purity requirements (e.g., ≥98% or ≥99%) for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.