Description

Pyrrolo[1,2-A]Pyrazine-1,4-Dione, Hexahydro-3-(Hydroxymethyl)-, (3R-Cis)- (9Ci) is a high-purity, stereochemically defined heterocyclic compound that serves as a critical chiral building block in advanced organic synthesis. Its value lies in its complex fused-ring structure and functional groups, which enable the construction of sophisticated molecular architectures with precise three-dimensional control. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly for applications requiring specific stereochemistry. The compound, identified by CAS No. 155322-95-5, is supplied under stringent quality control to ensure batch-to-batch consistency for demanding R&D and scale-up processes.

Application

This specialized chiral intermediate is utilized in the synthesis of complex bioactive molecules. Key application areas include:

• Pharmaceutical Intermediate: Serves as a key chiral scaffold in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Synthesis: Used in constructing advanced active ingredients for crop protection products, where stereochemistry can significantly influence biological activity.
• Chemical Biology & Medicinal Chemistry: Acts as a versatile building block for creating focused libraries of compounds in structure-activity relationship (SAR) studies.
• Asymmetric Synthesis Catalyst/ Ligand Precursor: Its defined stereocenter makes it a potential precursor for novel chiral ligands or organocatalysts.
• Advanced Material Research: Investigated for incorporation into specialty polymers or organic electronic materials requiring specific molecular geometries.

Basic Information

Product Name	Pyrrolo[1,2-A]Pyrazine-1,4-Dione, Hexahydro-3-(Hydroxymethyl)-, (3R-Cis)- (9Ci)
CAS No.	155322-95-5
Molecular Formula	C8H12N2O3
Molecular Weight	184.19 g/mol
Synonyms	(3R,3aR,6aS)-3-(Hydroxymethyl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione; Hexahydro-3-(hydroxymethyl)-, (3R-cis)-Pyrrolo[1,2-a]pyrazine-1,4-dione; (3R,3aR,6aS)-Octahydro-2H-pyrrolo[1,2-a]pyrazine-1,4-dione-3-methanol; (3R-cis)-Hexahydro-3-(hydroxymethyl)pyrrolo[1,2-a]pyrazine-1,4-dione; 3R-CIS-HEXAHYDRO-3-(HYDROXYMETHYL)PYRROLO[1,2-A]PYRAZINE-1,4-DIONE; Chiral Pyrrolopyrazinedione Derivative
EINECS	Contact for details

Quality Control

Our production of Pyrrolo[1,2-A]Pyrazine-1,4-Dione, Hexahydro-3-(Hydroxymethyl)-, (3R-Cis)- (9Ci) adheres to a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the high standards required for pharmaceutical and advanced chemical synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed when not in use to protect from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.