Description

2-Piperazinemethanol,5-(1-Methylethyl)-,(2S-Trans)-(9Ci) is a chiral piperazine derivative, a sophisticated building block of significant interest in advanced organic synthesis. Its value lies in its stereochemically defined structure, which is critical for imparting specific biological activity and selectivity in final compounds. This high-purity intermediate is primarily needed by pharmaceutical R&D and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially for central nervous system (CNS) and cardiovascular targets.
• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to create enantiomerically pure compounds.
• Agrochemical Research: Used in the synthesis of advanced, stereospecific pesticides and herbicides where specific isomer activity is required.
• Complex Molecule Construction: Serves as a versatile building block for constructing complex nitrogen-containing heterocycles in medicinal chemistry.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and receptor interactions.

Basic Information

Product Name	2-Piperazinemethanol,5-(1-Methylethyl)-,(2S-Trans)-(9Ci)
CAS No.	155322-94-4
Molecular Formula	C8H18N2O
Molecular Weight	158.24 g/mol
Synonyms	(2S-trans)-5-Isopropyl-2-piperazinemethanol; (2S,5S)-5-Isopropyl-2-piperazinemethanol; (2S-trans)-5-(1-Methylethyl)-2-piperazinemethanol; (2S,5S)-5-(1-Methylethyl)-2-piperazinemethanol; (2S,5S)-5-Isopropylpiperazin-2-ylmethanol; (2S,5S)-5-(Propan-2-yl)piperazin-2-ylmethanol; trans-(2S,5S)-5-Isopropyl-2-piperazinemethanol; Chiral Piperazine Methanol Derivative
EINECS	Contact for details

Quality Control

Our 2-Piperazinemethanol,5-(1-Methylethyl)-,(2S-Trans)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if specified for high-purity grades.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.