Description

2-Piperazinemethanol,5-(2-Methylpropyl)-,(2R-Cis)-(9Ci) is a specialized chiral piperazine derivative, a high-value intermediate critical for the synthesis of complex pharmaceutical compounds. Its precise stereochemistry and functional groups make it an essential building block for medicinal chemistry research and development, enabling the creation of targeted active pharmaceutical ingredients (APIs). This compound is primarily utilized by research institutions and pharmaceutical manufacturers focused on developing novel therapeutics, particularly in areas requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs), especially for central nervous system (CNS) and cardiovascular targets.
• Medicinal Chemistry Research: Used in drug discovery and lead optimization programs to explore structure-activity relationships (SAR) and develop new chemical entities.
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands used in homogeneous catalysis and metal-organic frameworks.
• Fine Chemical Production: Utilized in the multi-step synthesis of other high-purity, complex fine chemicals and specialty materials.

Basic Information

Item	Detail
Product Name	2-Piperazinemethanol,5-(2-Methylpropyl)-,(2R-Cis)-(9Ci)
CAS No.	155225-21-1
Molecular Formula	C9H20N2O
Molecular Weight	172.27 g/mol
Synonyms	(2R,5S)-5-Isobutyl-2-piperazinemethanol; (2R,5S)-5-(2-Methylpropyl)-2-piperazinemethanol; (2R-cis)-5-(2-Methylpropyl)-2-piperazinemethanol; cis-5-Isobutyl-2-piperazinemethanol (2R,5S)-isomer; 2-Piperazinemethanol, 5-(2-methylpropyl)-, (2R,5S)-; A chiral piperazine methanol derivative
EINECS	Contact for details

Quality Control

Every batch of 2-Piperazinemethanol,5-(2-Methylpropyl)-,(2R-Cis)-(9Ci) is manufactured under strict quality management systems. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles verified by techniques such as HPLC, GC, and chiral analysis. Our quality commitment ensures the material meets the stringent requirements for pharmaceutical R&D and cGMP intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.