Description

2-Piperazinemethanol,5-(1-Methylethyl)-,(2R-Cis)-(9Ci) is a chiral piperazine derivative, a sophisticated organic building block of significant value in advanced chemical synthesis. Its precise stereochemistry and functional groups make it a critical intermediate for creating molecules with specific biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals where stereochemical purity is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel therapeutic agents, including potential central nervous system (CNS) drugs and receptor modulators.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where the specific stereoisomer can influence biological efficacy and environmental profile.
• Catalyst Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in asymmetric catalysis to produce enantiomerically pure compounds.
• Fine Chemical Building Block: Employed in custom synthesis and contract manufacturing for creating complex, high-value specialty chemicals.
• Academic & R&D: Utilized in university and corporate research laboratories for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Item	Details
Product Name	2-Piperazinemethanol,5-(1-Methylethyl)-,(2R-Cis)-(9Ci)
CAS No.	155225-20-0
Molecular Formula	C8H18N2O
Molecular Weight	158.24 g/mol
Synonyms	(2R,5S)-2-(Hydroxymethyl)-5-isopropylpiperazine; (2R-cis)-5-Isopropyl-2-piperazinemethanol; cis-2-(Hydroxymethyl)-5-isopropylpiperazine; 5-Isopropyl-2-piperazinemethanol (cis-); (2R,5S)-5-Isopropyl-2-piperazinemethanol; (2R,5S)-2-(Hydroxymethyl)-5-(propan-2-yl)piperazine
EINECS	Contact for details

Quality Control

Our production of 2-Piperazinemethanol,5-(1-Methylethyl)-,(2R-Cis)-(9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chiral purity. Each lot is characterized and tested using advanced analytical techniques including HPLC, GC, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity (assay), enantiomeric excess, and impurity profiles is provided with every shipment, supporting cGMP and ISO 9001 standards for traceability and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.