Description

tert-Butyl 4-(2-Fluoro-4-Nitrophenyl)Piperazine-1-Carboxylate is a high-purity, protected piperazine derivative featuring a fluoronitrophenyl substituent, serving as a critical synthetic intermediate in modern organic chemistry. Its core value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs). This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors who require reliable, high-quality building blocks for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the fluoronitrophenyl moiety for bioactivity.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating labeled compounds or probes used in biochemical and pharmacological studies.
• Material Science Precursor: Can be utilized in the synthesis of specialty polymers or organic electronic materials where specific aromatic and heterocyclic structures are required.
• Custom Synthesis & Contract Manufacturing: An important starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic & R&D Laboratories: Employed in university and institutional research for methodological development and exploring new chemical reactions.

Basic Information

Product Name	tert-Butyl 4-(2-Fluoro-4-Nitrophenyl)Piperazine-1-Carboxylate
CAS No.	154590-34-8
Molecular Formula	C15H20FN3O4
Molecular Weight	325.34 g/mol
Synonyms	1-Boc-4-(2-Fluoro-4-nitrophenyl)piperazine; tert-Butyl 4-(2-fluoro-4-nitrophenyl)-1-piperazinecarboxylate; 1-(tert-Butoxycarbonyl)-4-(2-fluoro-4-nitrophenyl)piperazine; Boc-4-(2-Fluoro-4-nitrophenyl)piperazine; N-Boc-4-(2-Fluoro-4-nitrophenyl)piperazine; 4-(2-Fluoro-4-nitrophenyl)piperazine-1-carboxylic acid tert-butyl ester; 154590-34-8 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(2-Fluoro-4-Nitrophenyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 1.0%
Total Impurities	≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.