Description

1-(2-Fluoro-4-Nitrophenyl)Piperazine is a high-purity fluorinated nitrophenylpiperazine derivative, a key advanced pharmaceutical intermediate (API) and versatile building block for organic synthesis. Its molecular structure, featuring both electron-withdrawing nitro and fluoro substituents on the aromatic ring, makes it a critical precursor for developing active pharmaceutical ingredients (APIs) and fine chemicals. This compound is essential for research and production in pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and psychiatric therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its fluorinated aromatic structure.
• Ligand and Catalyst Development: Serves as a precursor for creating complex ligands used in catalytic processes and material science.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and dyes.

Basic Information

Product Name	1-(2-Fluoro-4-Nitrophenyl)Piperazine
CAS No.	154590-33-7
Molecular Formula	C10H12FN3O2
Molecular Weight	225.22 g/mol
Synonyms	1-(2-Fluoro-4-nitrophenyl)piperazine; 2-Fluoro-4-nitro-1-piperazinobenzene; 1-(2-Fluoro-4-nitrophenyl)piperazine; Piperazine, 1-(2-fluoro-4-nitrophenyl)-; 154590-33-7; 2-Fluoro-4-nitrophenylpiperazine; 4-Nitro-2-fluorophenylpiperazine; 1-(4-Nitro-2-fluorophenyl)piperazine
EINECS	Contact for details

Quality Control

Our 1-(2-Fluoro-4-Nitrophenyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.