Description

8-Methyl-2,8-Diazaspiro[4.5]Decan-3-One is a high-purity, advanced pharmaceutical intermediate belonging to the spirocyclic amine class of heterocyclic compounds. Its unique bridged bicyclic structure makes it a valuable scaffold for medicinal chemistry, particularly in the development of novel active pharmaceutical ingredients (APIs). This compound is primarily sought by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for synthesizing new drug candidates and specialty molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential central nervous system (CNS) and other therapeutic agents.
• Medicinal Chemistry Research: Used as a privileged scaffold in drug discovery programs for creating libraries of novel compounds with spirocyclic architectures.
• Agrochemical Synthesis: Serves as a precursor in the development of new crop protection agents and pesticides.
• Ligand and Catalyst Development: Utilized in the creation of specialized ligands for catalysis and molecular recognition applications.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	8-Methyl-2,8-Diazaspiro[4.5]Decan-3-One
CAS No.	154495-67-7
Molecular Formula	C9H16N2O
Molecular Weight	168.24 g/mol
Synonyms	8-Methyl-2,8-diazaspiro[4.5]decan-3-one; 2,8-Diazaspiro[4.5]decan-3-one, 8-methyl-; 8-Methyl-2,8-diazaspiro[4.5]decan-3-one; Spirocyclic amine intermediate; 154495-67-7; 8-Methyl-2,8-diazaspiro[4.5]decan-3-one (CAS 154495-67-7)
EINECS	Contact for details

Quality Control

Our 8-Methyl-2,8-Diazaspiro[4.5]Decan-3-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.