Description

5-Amino-Piperidin-2-One Hcl is a high-purity pharmaceutical intermediate and versatile organic building block. This compound is critical for the synthesis of complex molecules, offering a reactive amino group and a lactam moiety for further functionalization. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of protease inhibitors, neurological agents, and other bioactive molecules.
• Organic Synthesis Reagent: Used as a precursor for constructing complex piperidine-based heterocycles and chiral auxiliaries.
• Agrochemical Research: Serves as a starting material in the development of novel herbicides and pesticides.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme function.
• Custom Synthesis: A foundational component for contract research organizations (CROs) and CDMOs engaged in custom chemical synthesis projects.

Basic Information

Product Name	5-Amino-Piperidin-2-One Hcl
CAS No.	154148-70-6
Molecular Formula	C5H11N2O•HCl
Molecular Weight	150.62 g/mol (Free base: 114.16 g/mol)
Synonyms	5-Aminopiperidin-2-one hydrochloride; 2-Piperidinone, 5-amino-, hydrochloride; 5-Amino-2-piperidinone hydrochloride; 5-Amino-δ-valerolactam hydrochloride; 5-Aminopiperidin-2-one HCl; 5-Amino-2-oxopiperidine hydrochloride; 154148-70-6; 5-Amino-2-piperidone HCl
EINECS	Contact for details

Quality Control

Our 5-Amino-Piperidin-2-One Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.