Description

S-Acetyl-Peg3-Alcohol CAS NO 153870-20-3 is a high-purity, functionalized polyethylene glycol (PEG) derivative featuring a terminal acetyl-protected hydroxyl group. This compound is a critical intermediate for the synthesis of complex molecules, offering a versatile handle for conjugation and further chemical modification. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for applications such as linker synthesis, bioconjugation, and polymer chemistry.

Application

• Pharmaceutical Linker Synthesis: A key building block for creating cleavable or non-cleavable linkers used in antibody-drug conjugates (ADCs) and other targeted therapeutics.
• Bioconjugation Reagent: Used to functionalize peptides, proteins, and oligonucleotides with PEG chains to improve solubility, stability, and pharmacokinetic properties.
• Polymer Chemistry Intermediate: Serves as a monomer or initiator for the synthesis of specialized PEG-based copolymers and dendrimers.
• Proteomics Research: Employed in the development of chemical probes and affinity tags for studying protein function and interactions.
• Surface Modification: Used to create hydrophilic, non-fouling coatings on biomedical devices and diagnostic platforms.
• Cross-linking Agent: Acts as a spacer arm in the preparation of hydrogels and other cross-linked biomaterials.

Basic Information

Product Name	S-Acetyl-Peg3-Alcohol
CAS No.	153870-20-3
Molecular Formula	C11H22O6
Molecular Weight	250.29 g/mol
Synonyms	2-[2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy]ethyl acetate; 3,6,9-Trioxaundecan-1-ol, 11-acetate; Acetic acid 2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl ester; S-Acetyl-PEG3-OH; Ac-PEG3-OH; 11-Acetoxy-3,6,9-trioxaundecan-1-ol; PEG3 monoacetate; Tetraethylene glycol monoacetate
EINECS	Contact for details

Quality Control

Our S-Acetyl-Peg3-Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.