Description

tert-Butyl 4-Carbamimidoylpiperazine-1-Carboxylate is a high-purity, protected piperazine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role as a versatile intermediate in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and pesticides requiring specific piperazine-based scaffolds.
• Chemical Biology & Proteomics: Employed as a building block for designing chemical probes, enzyme inhibitors, and activity-based protein profiling (ABPP) reagents.
• Peptidomimetic Research: Facilitates the creation of peptide analogs and mimetics by introducing a guanidine-like functionality within a constrained ring system.
• Material Science: Acts as a monomer or cross-linking agent in the synthesis of specialized polymers and functional materials.

Basic Information

Product Name	tert-Butyl 4-Carbamimidoylpiperazine-1-Carboxylate
CAS No.	153836-14-7
Molecular Formula	C10H20N4O2
Molecular Weight	228.29 g/mol
Synonyms	1-Boc-4-carbamimidoylpiperazine; 4-(tert-Butoxycarbonyl)piperazine-1-carboximidamide; tert-Butyl 4-(carbamimidoyl)piperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-carbamimidoylpiperazine; 1-Boc-piperazine-4-carboximidamide; 4-Carbamimidoylpiperazine-1-carboxylic acid tert-butyl ester; 153836-14-7; N-Boc-4-carbamimidoylpiperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Carbamimidoylpiperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee batch-to-batch consistency and support your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.