Description

2-Bromo-5-(4-Fluorophenyl)Pyrazine is a high-purity, halogenated pyrazine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel active pharmaceutical ingredients (APIs) and functional materials. Pharmaceutical researchers, agrochemical developers, and specialty chemical manufacturers need this precise intermediate to facilitate key coupling and functionalization reactions in their R&D and production processes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, leveraging the bioactivity of the pyrazine core.
• Material Science Research: Serves as a monomer or functional unit in the creation of organic electronic materials, such as semiconductors for OLEDs.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and cross-coupling reactions.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and tags used in biochemical assay development.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up services for clients in the fine chemical industry.

Basic Information

Item	Details
Product Name	2-Bromo-5-(4-Fluorophenyl)Pyrazine
CAS No.	153295-35-3
Molecular Formula	C10H6BrFN2
Molecular Weight	253.07 g/mol
Synonyms	2-Bromo-5-(4-fluorophenyl)pyrazine; 5-(4-Fluorophenyl)-2-bromopyrazine; 2-Bromo-5-(p-fluorophenyl)pyrazine; (4-Fluorophenyl)-5-bromopyrazine; 153295-35-3; 2-Bromo-5-(4'-fluorophenyl)pyrazine; Pyrazine, 2-bromo-5-(4-fluorophenyl)-
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-(4-Fluorophenyl)Pyrazine is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard grade meets high-purity specifications suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Specifications can be developed to meet cGMP or other stringent regulatory requirements for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.