Description

1-(4-Nitro-3-Trifluoromethylphenyl)-Piperazine is a high-value, multi-functional aromatic piperazine derivative characterized by its nitro and trifluoromethyl substituents. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in modern synthetic chemistry. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of bioactive molecules, particularly for central nervous system (CNS) targeted drugs and receptor modulators.
• Agrochemical Research: Building block for developing new-generation herbicides and pesticides, leveraging the biological activity of the piperazine and fluorinated aryl motifs.
• Organic Synthesis Reagent: Used in coupling reactions and as a ligand or catalyst component in metal-organic chemistry.
• Material Science: Intermediate for creating specialty polymers, dyes, and functional materials requiring fluorinated aromatic units.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	1-(4-Nitro-3-Trifluoromethylphenyl)-Piperazine
CAS No.	153204-82-1
Molecular Formula	C11H12F3N3O2
Molecular Weight	275.23 g/mol
Synonyms	1-(4-Nitro-3-(trifluoromethyl)phenyl)piperazine; 4-Nitro-3-(trifluoromethyl)phenylpiperazine; 1-(4-Nitro-alpha,alpha,α-trifluoro-m-tolyl)piperazine; 4-Nitro-3-trifluoromethyl-1-piperazinobenzene; Piperazine, 1-[4-nitro-3-(trifluoromethyl)phenyl]-; 153204-82-1; 1-(4-Nitro-3-trifluoromethylphenyl)piperazine
EINECS	Contact for details

Quality Control

Our production of 1-(4-Nitro-3-Trifluoromethylphenyl)-Piperazine adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound should be kept under an inert atmosphere if long-term storage is required to minimize potential degradation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.