Description

(4R,5S,6S,7R)-4,7-Dibenzyl-1,3-Bis[(3-Fluorophenyl)Methyl]-5,6-Dihydro Xy-1,3-Diazepan-2-One is a sophisticated, high-purity chiral diazepanone derivative, serving as a critical advanced pharmaceutical intermediate (API) and a valuable scaffold in medicinal chemistry. Its complex stereochemistry and functional groups make it an essential building block for the research and development of novel therapeutic agents. This compound is primarily targeted at pharmaceutical R&D and fine chemical synthesis sectors, where precise molecular architecture is paramount.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis to discover new bioactive molecules.
• Asymmetric Synthesis: Employed in catalytic and stoichiometric asymmetric reactions due to its defined stereocenters, aiding in the production of enantiomerically pure compounds.
• Chemical Biology Probes: Utilized in the development of molecular probes to study enzyme mechanisms and protein-ligand interactions.
• Process Chemistry Development: Serves as a model compound for scaling up and optimizing synthetic routes under current Good Manufacturing Practice (cGMP) guidelines.
• Academic & Institutional Research: A valuable reagent for universities and research institutes focusing on organic methodology and heterocyclic chemistry.

Basic Information

Product Name	(4R,5S,6S,7R)-4,7-Dibenzyl-1,3-Bis[(3-Fluorophenyl)Methyl]-5,6-Dihydro Xy-1,3-Diazepan-2-One
CAS No.	153182-42-4
Molecular Formula	C33H30F2N2O
Molecular Weight	508.61 g/mol
Synonyms	1,3-Diazepan-2-one, 4,7-dibenzyl-1,3-bis[(3-fluorophenyl)methyl]-5,6-dihydro-, (4R,5S,6S,7R)-; (4R,5S,6S,7R)-4,7-Dibenzyl-1,3-bis(3-fluorobenzyl)-5,6-dihydroxy-1,3-diazepan-2-one; 153182-42-4; Chiral Diazepanone Derivative; Fluorinated Benzyl Diazepanone; Advanced Chiral Intermediate
EINECS	Contact for details

Quality Control

Every batch of this high-value intermediate is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with each shipment. Our quality protocols are designed to support cGMP-compliant applications in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); ensure the container is sealed under an inert atmosphere if opened. Keep away from strong acids/bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.