Description

(4R,5S,6S,7R)-4,7-Dibenzyl-5,6-Dihydroxy-1,3-Dipentyl-1,3-Diazepan-2-One is a high-purity, chiral diazepanone derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated chemical building block for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications requiring precise stereochemical control.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drug candidates.
• Asymmetric Catalysis Ligand Synthesis: Used in the development of novel chiral ligands and organocatalysts for enantioselective transformations.
• Agrochemical Research: Employed as a building block for creating new chiral molecules with potential herbicidal or insecticidal activity.
• Academic & Institutional R&D: A valuable compound for methodological studies in organic chemistry, heterocycle synthesis, and stereochemistry.
• Fine Chemical Synthesis: Utilized in the custom synthesis of specialty chemicals, flavors, and fragrances requiring specific stereoisomers.
• Process Chemistry Development: Acts as a model substrate for scaling up and optimizing synthetic routes under current Good Manufacturing Practice (cGMP) guidelines.

Basic Information

Product Name	(4R,5S,6S,7R)-4,7-Dibenzyl-5,6-Dihydroxy-1,3-Dipentyl-1,3-Diazepan-2-One
CAS No.	153181-48-7
Molecular Formula	C31H44N2O3
Molecular Weight	492.70 g/mol
Synonyms	1,3-Diazepan-2-one, 4,7-bis(phenylmethyl)-5,6-dihydroxy-1,3-dipentyl-, (4R,5S,6S,7R)-; (4R,5S,6S,7R)-4,7-Bis(benzyl)-5,6-dihydroxy-1,3-dipentyl-1,3-diazepan-2-one; Chiral Diazepanone Derivative; 1,3-Dipentyl-4,7-dibenzyl-5,6-dihydroxy-1,3-diazepan-2-one; 153181-48-7; 4,7-Dibenzyl-5,6-dihydroxy-1,3-dipentylperhydro-1,3-diazepin-2-one
EINECS	Contact for details

Quality Control

Our (4R,5S,6S,7R)-4,7-Dibenzyl-5,6-Dihydroxy-1,3-Dipentyl-1,3-Diazepan-2-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for chiral purity and assay, NMR for structural confirmation, and specific optical rotation measurement to ensure stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere (e.g., nitrogen or argon) in a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Specific Optical Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.