Description

Para-Iodophenyl Hoe 140 is a specialized iodinated aromatic compound, identified by CAS No. 152221-57-3, serving as a key intermediate in advanced organic synthesis. This compound is valued for its precise chemical structure, which enables the introduction of iodine and specific functional groups into target molecules. It is primarily sought by research institutions and pharmaceutical developers for applications in medicinal chemistry, including the synthesis of potential drug candidates and biochemical probes.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs) and investigational drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and for creating targeted molecular libraries.
• Bioconjugation & Probe Development: Serves as a precursor for radiolabeling or fluorescent tagging agents used in biochemical assays and diagnostic imaging.
• Organic Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) to construct complex, functionalized aromatic systems.
• Material Science Precursor: Can be utilized in the development of specialty polymers and advanced organic electronic materials.

Basic Information

Product Name	Para-Iodophenyl Hoe 140
CAS No.	152221-57-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Hoe 140 (para-iodophenyl derivative); 4-Iodophenyl Hoe 140; 1-[N2-[(1S)-1-Carboxy-3-(4-iodophenyl)propyl]-L-lysyl]-L-proline derivative; Bradykinin B2 receptor antagonist intermediate; Icatibant intermediate; (2R)-2-[[(2S)-6-Amino-2-[[(2S)-1-[(2S)-2-[(4-iodophenyl)methyl]-3-oxo-3-[(2S)-pyrrolidin-2-yl]propyl]amino]hexanoyl]amino]hexanoic acid derivative
EINECS	Contact for details

Quality Control

Our Para-Iodophenyl Hoe 140 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Quality is verified through a comprehensive suite of analytical techniques including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.