Description

Uroporphyrin Iii Dihydrochloride is a high-purity porphyrin derivative essential for biochemical research and diagnostic applications. This compound serves as a critical reference standard and precursor in the study of heme biosynthesis and porphyria disorders. It is primarily utilized by research institutions, pharmaceutical R&D departments, and in vitro diagnostic (IVD) kit manufacturers requiring precise and reliable biochemical reagents.

Application

• Biochemical Research: Used as a key intermediate and reference standard in studies of porphyrin metabolism and heme biosynthesis pathways.
• Diagnostic Reagent Manufacturing: Serves as a critical raw material in the production of calibrators and controls for porphyria testing kits.
• Enzyme Activity Assays: Employed as a substrate in enzymatic assays for uroporphyrinogen decarboxylase and other related enzymes.
• Pharmaceutical Development: Acts as a starting material or reference compound in the research of therapies targeting metabolic disorders.
• Analytical Chemistry: Used as a high-purity standard for HPLC, LC-MS, and other analytical method development and validation.
• Photodynamic Therapy (PDT) Research: Investigated for its potential photosensitizing properties in preclinical studies.

Basic Information

Product Name	Uroporphyrin Iii Dihydrochloride
CAS No.	150957-29-2
Molecular Formula	C₄₀H₄₂N₄O₁₆ • 2HCl
Molecular Weight	883.70 g/mol (for free acid, dihydrochloride salt weight varies)
Synonyms	Uroporphyrin III dihydrochloride; Uroporphyrin III HCl; Uroporphyrin 3 dihydrochloride; 3,8,13,17-Tetrakis(2-carboxyethyl)-2,7,12,18-tetramethylporphyrin dihydrochloride; URO III 2HCl; Uro'gen III derivative; Porphyrin VIII isomer dihydrochloride
EINECS	Contact for details

Quality Control

Our Uroporphyrin Iii Dihydrochloride is manufactured under controlled conditions to ensure batch-to-batch consistency and high purity suitable for research and diagnostic use. Each lot undergoes rigorous analytical testing, including HPLC for purity assessment and identity confirmation via UV-Vis and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to ensure traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. Due to its hygroscopic nature, the container should be allowed to reach room temperature before opening to minimize moisture uptake. For long-term storage, consider desiccants or under an inert atmosphere.

Specification

Item	Specification
Appearance	Dark red to purple powder
Identification (HPLC)	Conforms to reference standard
Identification (UV-Vis)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in dilute alkali, DMSO; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.