Description

n-[2-[[[4-(2,2-Dimethyl-1-Oxopropoxy)Phenyl]Sulfonyl]Amino]Benzoyl]-(S)-Glycine Monosodium Salt is a high-purity, single-enantiomer chemical intermediate of significant importance in advanced pharmaceutical synthesis. Its value lies in its role as a key building block for the development of novel therapeutic agents, particularly those targeting specific biological pathways with high selectivity. This compound is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the discovery and production of new drugs.

Application

• Pharmaceutical Intermediate: A critical chiral building block in the synthesis of active pharmaceutical ingredients (APIs), especially for protease inhibitors and other enzyme-targeted therapies.
• Protease Inhibitor Synthesis: Serves as a core structural component in the development of novel protease inhibitors for treating viral infections and other diseases.
• Chiral Synthesis: Utilized in asymmetric synthesis and medicinal chemistry research to introduce specific stereochemistry into complex molecules.
• Biochemical Research: Employed as a reference standard or tool compound in biochemical assays and pharmacological studies.
• Preclinical Drug Development: Used in the scale-up and process optimization stages for new chemical entities (NCEs) during preclinical development.

Basic Information

Item	Detail
Product Name	n-[2-[[[4-(2,2-Dimethyl-1-Oxopropoxy)Phenyl]Sulfonyl]Amino]Benzoyl]-(S)-Glycine Monosodium Salt
CAS No.	150374-95-1
Molecular Formula	C20H21N2NaO7S
Molecular Weight	456.44 g/mol
Synonyms	(S)-Glycine, N-[2-[[[4-[(2,2-dimethyl-1-oxopropoxy)]phenyl]sulfonyl]amino]benzoyl]-, monosodium salt; Monosodium N-[2-[[[4-(pivaloyloxy)phenyl]sulfonyl]amino]benzoyl]-(S)-glycinate; (S)-N-(2-((4-(Pivaloyloxy)phenyl)sulfonamido)benzoyl)glycine sodium salt; Pivaloyl Oxobenzene Glycine Sodium Salt; A key intermediate for protease inhibitors; Contact for additional trade names and abbreviations.
EINECS	Contact for details

Quality Control

Our n-[2-[[[4-(2,2-Dimethyl-1-Oxopropoxy)Phenyl]Sulfonyl]Amino]Benzoyl]-(S)-Glycine Monosodium Salt is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity suitable for pharmaceutical R&D. Production adheres to current industry best practices, and comprehensive analytical testing is performed. A Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles is provided with each shipment to support your regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% (S-enantiomer)
Water Content (KF)	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.