Description

(S)-2-tert-Butylcarboxamide-4-tert-Butoxycarbonyl Piperazine CAS NO 150323-35-6 is a high-purity, chiral piperazine derivative used as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. Pharmaceutical researchers and fine chemical manufacturers need it for creating novel therapeutic agents, where its defined stereochemistry and protected functional groups are essential for precise chemical transformations.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Peptidomimetic Synthesis: Serves as a constrained scaffold for designing and synthesizing peptide mimics with enhanced metabolic stability and bioavailability.
• Asymmetric Catalysis Ligand Precursor: Used in the preparation of chiral ligands for asymmetric hydrogenation and other enantioselective catalytic reactions.
• API Process Development: Employed in scale-up and process chemistry for the commercial manufacturing of chiral active pharmaceutical ingredients.
• Custom Chemical Synthesis: A versatile building block for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.
• Agrochemical Research: Utilized in the discovery of novel, chiral agrochemicals with specific biological activity.

Basic Information

Product Name	(S)-2-tert-Butylcarboxamide-4-tert-Butoxycarbonyl Piperazine
CAS No.	150323-35-6
Molecular Formula	C14H27N3O3
Molecular Weight	285.38 g/mol
Synonyms	(S)-1-Boc-2-(tert-Butylcarboxamido)piperazine; (S)-1-(tert-Butoxycarbonyl)-2-(tert-butylcarbamoyl)piperazine; (S)-N-tert-Butyl-1-(tert-butoxycarbonyl)piperazine-2-carboxamide; (S)-2-(tert-Butylcarbamoyl)-1-Boc-piperazine; (S)-1-Boc-2-(N-tert-butylcarbamoyl)piperazine; (S)-1-Boc-piperazine-2-carboxylic acid tert-butylamide; (S)-2-(tert-Butylaminocarbonyl)-4-(tert-butoxycarbonyl)piperazine
EINECS	Contact for details

Quality Control

Our (S)-2-tert-Butylcarboxamide-4-tert-Butoxycarbonyl Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and NMR for structural confirmation, to ensure compliance with high-purity standards for pharmaceutical research. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.