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1,2-Di-o-Phytanyl-Sn-Glycero-3-Phosphoethanolamine CAS NO 150135-14-1


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CAS No.:150135-14-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,2-Di-o-Phytanyl-Sn-Glycero-3-Phosphoethanolamine is a high-purity synthetic phospholipid derivative, specifically an archaeal lipid analog. This compound is critical for creating stable, biomimetic membrane systems that are highly resistant to extreme environmental conditions. It is an essential material for researchers and manufacturers in advanced biotechnology, pharmaceutical formulation, and nanotechnology who require robust and reliable membrane components for demanding applications.

Application

  • Liposome and Vesicle Formation: A key component for constructing archaeosome-based drug delivery systems with enhanced stability and unique targeting properties.
  • Biomimetic Membrane Research: Used to create model membranes that mimic the unique, ether-linked lipid structures found in extremophilic archaea for studying membrane biophysics and protein-lipid interactions.
  • Stabilization of Membrane Proteins: Employed to solubilize and stabilize integral membrane proteins, such as G-protein coupled receptors (GPCRs), for structural biology and functional assays.
  • Biosensor Development: Incorporated into lipid bilayers for electrochemical and optical biosensors to improve longevity and performance under harsh operating conditions.
  • Cosmetic and Dermal Formulations: Acts as a premium skin-compatible lipid for advanced cosmetic products aiming to improve skin barrier function and delivery of active ingredients.
  • Vaccine Adjuvant Systems: Investigated for use in novel adjuvant platforms due to the immunostimulatory potential and biodegradability of archaeal lipid structures.

Basic Information

Product Name 1,2-Di-o-Phytanyl-Sn-Glycero-3-Phosphoethanolamine
CAS No. 150135-14-1
Molecular Formula C48H98NO6P
Molecular Weight 816.26 g/mol
Synonyms DPhyPE; Archaeal PE Lipid; 1,2-Diphytanyl-sn-glycero-3-phosphoethanolamine; Diphytanylphosphatidylethanolamine; DPhyPE (DOEPE); PE-C20,20 diether; Diether Phosphatidylethanolamine; 3-sn-Phosphatidylethanolamine, 1,2-di-O-phytanyl-
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Quality Control

Our 1,2-Di-o-Phytanyl-Sn-Glycero-3-Phosphoethanolamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, MS), to ensure it meets the stringent requirements for research and formulation. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) due to its hygroscopic and light-sensitive nature. For long-term storage, desiccate. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item Specification
Appearance White to off-white waxy solid or film
Identification (NMR) Conforms to structure
Identification (MS) Conforms to structure
Purity (HPLC) ≥ 95%
Solubility Soluble in chloroform, methanol, ethanol; forms vesicles in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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