Description

(R)-4-Benzyl-2-Hydroxymethylpiperazine is a chiral piperazine derivative of significant importance in advanced organic synthesis. This compound serves as a versatile and high-value building block for the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors, where its specific stereochemistry is critical for creating molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules, particularly those targeting neurological and cardiovascular systems.
• Asymmetric Catalyst Ligand: Used in the preparation of chiral ligands for metal-catalyzed asymmetric reactions, enhancing enantioselectivity.
• API Development: Serves as a core structural component in the research and development of new active pharmaceutical ingredients.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of specialty chemicals and complex organic compounds requiring high stereochemical purity.
• Bioconjugation & Linker Chemistry: The hydroxymethyl group provides a handle for further functionalization, useful in creating bioconjugates or chemical linkers.

Basic Information

Product Name	(R)-4-Benzyl-2-Hydroxymethylpiperazine
CAS No.	149715-46-8
Molecular Formula	C12H18N2O
Molecular Weight	206.29 g/mol
Synonyms	(R)-4-Benzyl-2-(hydroxymethyl)piperazine; (R)-1-Benzyl-3-(hydroxymethyl)piperazine; (2R)-4-Benzyl-2-(hydroxymethyl)piperazine; (R)-2-(Hydroxymethyl)-4-benzylpiperazine; (R)-4-Benzylpiperazine-2-methanol; (R)-Benzylhydroxymethylpiperazine; (R)-BHMP
EINECS	Contact for details

Quality Control

Our (R)-4-Benzyl-2-Hydroxymethylpiperazine is produced under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.