Description

3-Oxo-4-(Phenylmethyl)-2-Piperazinecarboxylic Acid Ethyl Ester is a high-purity pharmaceutical intermediate and building block of significant synthetic utility. Its piperazine core structure makes it a valuable precursor in the research and development of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking to synthesize complex molecules with high stereochemical and chemical purity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological disorders.
• API Synthesis: Used in the research, development, and scale-up production of Active Pharmaceutical Ingredients (APIs).
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals and advanced materials.
• Contract Research & Manufacturing (CRAM): Supplied to organizations offering custom synthesis and process development services.
• Academic & Institutional Research: Utilized in university and institutional labs for synthetic organic chemistry and pharmacological studies.

Basic Information

Product Name	3-Oxo-4-(Phenylmethyl)-2-Piperazinecarboxylic Acid Ethyl Ester
CAS No.	149648-71-5
Molecular Formula	C15H20N2O3
Molecular Weight	276.33 g/mol
Synonyms	Ethyl 3-oxo-4-benzylpiperazine-2-carboxylate; 4-Benzyl-3-oxopiperazine-2-carboxylic acid ethyl ester; 2-Piperazinecarboxylic acid, 3-oxo-4-(phenylmethyl)-, ethyl ester; 4-Benzyl-2-(ethoxycarbonyl)-3-oxopiperazine; 3-Oxo-4-benzyl-2-piperazinecarboxylic acid ethyl ester; Ethyl 4-benzyl-3-oxopiperazine-2-carboxylate
EINECS	Contact for details

Quality Control

Our 3-Oxo-4-(Phenylmethyl)-2-Piperazinecarboxylic Acid Ethyl Ester is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.