Description

Jaspisamide B CAS NO 149420-77-9 is a specialized bioactive marine natural product belonging to the jasplakinolide family of cyclic depsipeptides. This compound is of significant interest for its potent and selective biological activity, particularly as a cytoskeletal disruptor. It serves as a critical research tool for scientists in pharmacology, cell biology, and oncology, enabling the study of actin polymerization dynamics and cellular morphology. Its unique structure also makes it a valuable lead compound for the development of novel therapeutic agents.

Application

• Biomedical Research: As a potent actin filament stabilizer and disruptor of the cytoskeleton for studying cell motility, division, and morphology.
• Pharmacological Probe Development: Used as a reference standard and lead compound in drug discovery programs targeting cancer and other diseases involving cytoskeletal dysfunction.
• Cell Biology Studies: Essential for investigating fundamental cellular processes such as endocytosis, vesicle trafficking, and signal transduction pathways linked to the actin network.
• Oncology Research: Evaluation of anti-cancer properties, including the induction of apoptosis and inhibition of tumor cell proliferation and metastasis.
• Chemical Biology: Serves as a molecular tool for probing protein-protein interactions and validating new targets related to the actin cytoskeleton.
• High-Content Screening (HCS): Utilized in automated imaging assays to identify novel compounds that modulate actin dynamics.

Basic Information

Product Name	Jaspisamide B
CAS No.	149420-77-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Jaspamide B; Jasplakinolide B; Jaspisamide-B; NSC 613009; Cyclo[(2S,4E,6E,8R,10S)-10-hydroxy-2,4,6,8-tetramethyl-10-phenyldeca-4,6-dienoyl-L-phenylalanyl-N-methyl-L-valyl]
EINECS	Contact for details

Quality Control

Our Jaspisamide B is produced under stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for reliable research outcomes. Each lot undergoes comprehensive analytical characterization using techniques such as HPLC, NMR, and MS to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to relevant industry standards for research-grade biochemicals to support your scientific integrity.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store the product at -20°C or below. The container should be kept in a dry, cool, and well-ventilated area. Allow the product to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.