Description

1-Palmitoyl-2-Arachidonoylphosphatidylfluorouridine is a specialized, high-purity phospholipid-fluorouridine conjugate designed for advanced research and development. This compound is critical for studying membrane biophysics, targeted drug delivery mechanisms, and the modulation of cellular signaling pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on novel therapeutic platforms and diagnostic tools.

Application

• Lipid Nanoparticle (LNP) Formulation: A key synthetic lipid component for constructing advanced delivery systems for nucleic acids (mRNA, siRNA).
• Membrane Biophysics Research: Used as a probe or model compound to study lipid bilayer properties, phase behavior, and membrane-protein interactions.
• Targeted Drug Delivery: Serves as a functionalized building block for creating ligand-targeted liposomes and other nanocarriers.
• Biochemical Research: Employed in enzymatic studies and as a substrate or inhibitor for phospholipases and other lipid-metabolizing enzymes.
• Diagnostic Development: Potential use in the development of fluorescent or otherwise tagged probes for cellular imaging and diagnostic assays.

Basic Information

Product Name	1-Palmitoyl-2-Arachidonoylphosphatidylfluorouridine
CAS No.	148763-97-7
Molecular Formula	C52H80FN2O14P
Molecular Weight	1015.2 g/mol
Synonyms	1-Palmitoyl-2-arachidonoyl-sn-glycero-3-phosphofluorouridine; PAP-Fluorouridine; Phosphatidylfluorouridine (16:0/20:4); 1-Hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-5-fluorouridine; Fluorouridine-labeled phospholipid; 5-Fluorouridine phospholipid conjugate; sn-Glycero-3-phospho-5-fluorouridine 1-palmitoyl-2-arachidonoyl ester
EINECS	Contact for details

Quality Control

Our 1-Palmitoyl-2-Arachidonoylphosphatidylfluorouridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to ensure long-term stability. This material is hygroscopic (moisture-sensitive) and light-sensitive; allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid or film
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solvent Content (Residual Solvents)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.