Description

Methyl n-Boc-Piperidine-3-Carboxylate CAS NO 148763-41-1 is a high-purity, protected amino acid derivative widely used as a critical building block in advanced organic synthesis. This compound is essential for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and novel bioactive compounds. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for its role in peptide mimetics and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of piperidine-based drug candidates, including protease inhibitors and neurological agents.
• Peptidomimetics Research: Serves as a protected scaffold for constructing non-natural amino acids and peptide analogs in drug discovery.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides that require specific stereochemistry.
• Ligand and Catalyst Development: Employed in the creation of chiral ligands for asymmetric catalysis and organometallic complexes.
• Custom Chemical Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for clients.
• Academic Research: Utilized in university and institutional labs for methodological studies in organic chemistry and medicinal chemistry.

Basic Information

Product Name	Methyl n-Boc-Piperidine-3-Carboxylate
CAS No.	148763-41-1
Molecular Formula	C13H23NO4
Molecular Weight	257.33 g/mol
Synonyms	Methyl 1-Boc-3-piperidinecarboxylate; 1-(tert-Butoxycarbonyl)-3-piperidinecarboxylic acid methyl ester; Methyl 1-[(2-methyl-2-propanyl)oxycarbonyl]-3-piperidinecarboxylate; 3-Carbomethoxy-1-Boc-piperidine; 1-Boc-3-piperidinecarboxylic acid methyl ester; 1-N-Boc-3-piperidinecarboxylic acid methyl ester; tert-Butyl 3-(methoxycarbonyl)piperidine-1-carboxylate; Methyl piperidine-3-carboxylate, N-Boc protected.
EINECS	Contact for details

Quality Control

Our Methyl n-Boc-Piperidine-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with full traceability are provided for all shipments, confirming compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.