Description

6-Aminoquinolyl-n-Hydroxysuccinimidylcarbamate is a specialized active ester reagent primarily used for the derivatization of amines and amino acids to enhance their detection. This compound matters for its critical role in enabling highly sensitive analytical methods, particularly in high-performance liquid chromatography (HPLC) and mass spectrometry. It is essential for researchers and quality control laboratories in the pharmaceutical, biotechnology, and analytical chemistry sectors who require precise quantification of amino compounds.

Application

• Pre-column derivatization agent for amino acid analysis via HPLC with fluorescence or UV detection.
• Tagging reagent for enhancing the mass spectrometric sensitivity of peptides and primary amines.
• Biomarker research tool for the quantification of low-abundance amines in complex biological matrices.
• Pharmaceutical analysis for the assay of drug substances and impurities containing primary or secondary amino groups.
• Proteomics and metabolomics workflows for sample preparation and labeling.
• Quality control in the synthesis of peptides and other amino-functionalized APIs.

Basic Information

Product Name	6-Aminoquinolyl-n-Hydroxysuccinimidylcarbamate
CAS No.	148757-94-2
Molecular Formula	C19H16N4O5
Molecular Weight	380.35 g/mol
Synonyms	6-AQC; AQC; 6-Aminoquinolyl-N-hydroxysuccinimidyl Carbamate; AccQ•Fluor Reagent; AccQ•Tag Reagent; 6-Aminoquinoline-N-hydroxysuccinimidyl Carbamate; N-(6-Aminoquinolyl)-N'-succinimidyl Carbamate; N-Succinimidyl 6-Aminoquinolylcarbamate
EINECS	Contact for details

Quality Control

Our 6-Aminoquinolyl-n-Hydroxysuccinimidylcarbamate is manufactured under strict quality systems to ensure batch-to-batch consistency and high reactivity. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all specifications are available upon request to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below. This material is hygroscopic (moisture-sensitive); allow the sealed container to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in acetonitrile, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.