Description

n-[4-Methoxy-3-(4-Methyl-1-Piperazinyl)Phenyl]-2-Methyl-4-(5-Methyl-1,2,4-Oxadiazol-3-Yl)-1,1-Biphenyl-4-Carboxamide Hydrate Hydrochloride is a high-purity, non-peptidic small molecule compound of significant interest in advanced pharmaceutical research and development. Its complex structure, featuring a biphenyl core linked to piperazinyl and oxadiazole moieties, makes it a valuable intermediate for creating novel therapeutic agents. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery of new drug candidates. It is supplied as a hydrate hydrochloride salt to ensure stability and consistent handling properties.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Biochemical Research: Used as a reference standard or a tool compound in biochemical assays to study specific biological pathways and receptor interactions.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize lead compounds for improved potency, selectivity, and pharmacokinetic properties.
• High-Throughput Screening (HTS): Can be incorporated into compound libraries for screening against novel biological targets to identify potential drug leads.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of complex molecules for client projects.

Basic Information

Product Name	n-[4-Methoxy-3-(4-Methyl-1-Piperazinyl)Phenyl]-2-Methyl-4-(5-Methyl-1,2,4-Oxadiazol-3-Yl)-1,1-Biphenyl-4-Carboxamide Hydrate Hydrochloride
CAS No.	148642-42-6
Molecular Formula	C30H33N5O3 • HCl • xH2O
Molecular Weight	Contact for details
Synonyms	Biphenyl-4-carboxamide, N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)-, hydrate, hydrochloride; UNII-8V5Q8Q6VCE; 8V5Q8Q6VCE; BMS-378806 Hydrochloride Hydrate; BMS378806 Hydrochloride Hydrate; CCR5 Receptor Antagonist BMS-378806 Hydrochloride Hydrate
EINECS	Contact for details

Quality Control

Our n-[4-Methoxy-3-(4-Methyl-1-Piperazinyl)Phenyl]-2-Methyl-4-(5-Methyl-1,2,4-Oxadiazol-3-Yl)-1,1-Biphenyl-4-Carboxamide Hydrate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research-grade materials. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, water content (KF), and related substances.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	Contact for details
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.