Description

1,2-Dipalmitoyl-Sn-Glycero-3-Phospho-Cho Line Monohydrate is a high-purity synthetic phospholipid, specifically a fully saturated phosphatidylcholine. This compound is a critical building block for creating advanced lipid-based delivery systems and biomimetic membranes. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require precise and reliable lipid components for formulation development.

Application

• Liposome & Nanoparticle Formulation: A primary component for constructing stable, uniform liposomes used in drug delivery, mRNA vaccines, and diagnostic agents.
• Biomimetic Membrane Research: Used to create model cell membranes (e.g., supported lipid bilayers) for studying membrane protein interactions, permeability, and cellular mechanics.
• Excipient in Pharmaceutical Products: Serves as a functional excipient in solid dosage forms and injectables, enhancing bioavailability and stability of active pharmaceutical ingredients (APIs).
• Cell Culture & Biotechnology: Employed in serum-free media formulations and as a supplement to support specific cell growth and membrane function in vitro.
• Cosmetic & Dermal Delivery Systems: Incorporated into nanoemulsions and vesicles (niosomes) for targeted and sustained release of active ingredients in skincare products.
• Analytical Reference Standard: Used as a certified reference material (CRM) in quality control laboratories for HPLC, MS, or NMR method development and validation.

Basic Information

Product Name	1,2-Dipalmitoyl-Sn-Glycero-3-Phospho-Cho Line Monohydrate
CAS No.	148383-51-1
Molecular Formula	C40H82NO8P • H2O
Molecular Weight	758.06 g/mol (Anhydrous basis)
Synonyms	DPPC; 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine Monohydrate; L-α-Phosphatidylcholine, dipalmitoyl; Dipalmitoyl Phosphatidylcholine; Dipalmitoyl Lecithin; 1,2-Dihexadecanoyl-sn-glycero-3-phosphocholine; (2R)-2,3-Bis(hexadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate; Lecithin, dipalmitoyl
EINECS	Contact for details

Quality Control

Our 1,2-Dipalmitoyl-Sn-Glycero-3-Phospho-Cho Line Monohydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical and research applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and regulatory support.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive) and easily oxidized. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0% (Anhydrous basis)
Water Content (KF)	3.0 - 5.0 % (Theoretical for monohydrate ~4.8%)
Melting Point	Approx. 41 - 46 °C
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.