Description

n-Acetyl-D-Erythro-Sphingosylphosphorylcholine is a high-purity, synthetic sphingolipid derivative, specifically an acetylated form of sphingosylphosphorylcholine. This compound is a critical biochemical tool and a key intermediate in the study of sphingolipid metabolism and cell signaling pathways. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors who require well-defined, high-quality lipid standards for analytical, diagnostic, and therapeutic development purposes.

Application

• Biochemical Research Standard: Used as a high-purity reference standard in mass spectrometry (MS), nuclear magnetic resonance (NMR), and chromatography for the identification and quantification of sphingolipids.
• Cell Signaling Studies: Serves as a precursor or analog in research focused on sphingolipid-mediated cell processes, including apoptosis, proliferation, and stress responses.
• Enzyme Substrate: Acts as a specific substrate for studying the activity of enzymes like sphingomyelinases and other sphingolipid-metabolizing enzymes in vitro.
• Pharmaceutical Intermediates: Employed as a key building block in the synthesis of novel therapeutic agents targeting lipid-related disorders, such as cancer and neurodegenerative diseases.
• Diagnostic Development: Utilized in the development of diagnostic assays and kits for measuring sphingolipid levels in biological samples, relevant to metabolic disease research.
• Lipidomics: An indispensable component in lipidomics research for creating calibration curves and validating analytical methods to map complex lipid profiles.

Basic Information

Product Name	n-Acetyl-D-Erythro-Sphingosylphosphorylcholine
CAS No.	148306-05-2
Molecular Formula	C27H55N2O7P
Molecular Weight	550.71 g/mol
Synonyms	N-Acetylsphingosylphosphorylcholine; N-Acetyl-SPC; Acetyl Sphingosylphosphorylcholine; C2-Ceramide-1-Phosphocholine; N-Acetyl-D-erythro-sphingosine phosphocholine; N-Acetyl-sphingosine-1-phosphocholine; Lyso-N-acetyl-C2-ceramide; N-Acetyl sphingosylphosphorylcholine
EINECS	Contact for details

Quality Control

Every batch of n-Acetyl-D-Erythro-Sphingosylphosphorylcholine is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are suitable for research and development applications requiring high-grade lipid standards. A detailed Certificate of Analysis (COA) providing results for assay, purity (HPLC), and identification is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Allow the sealed vial to equilibrate to room temperature before opening to avoid condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in chloroform, methanol, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.