Description

Boc-3-Exo-Aminobicyclo[2.2.1]Hept-5-Ene-2-Exo-Carboxylic Acid is a high-purity, protected amino acid derivative featuring a rigid norbornene scaffold. This compound is a critical chiral building block in advanced organic synthesis, valued for its ability to introduce conformational constraint and stereochemical complexity into target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex natural product analogs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel drug candidates, particularly in protease inhibitor and peptide mimetic research.
• Peptidomimetic Chemistry: Used to construct conformationally restricted peptide backbones to enhance metabolic stability and receptor selectivity.
• Organocatalyst & Ligand Synthesis: Serves as a precursor for sophisticated chiral catalysts and ligands used in asymmetric synthesis.
• Agrochemical Research: Employed in the design and synthesis of new herbicides and insecticides with unique modes of action.
• Material Science: A potential monomer for creating specialty polymers with tailored thermal and mechanical properties.
• Academic & Discovery Research: A versatile tool in methodological studies and the total synthesis of complex natural products.

Basic Information

Product Name	Boc-3-Exo-Aminobicyclo[2.2.1]Hept-5-Ene-2-Exo-Carboxylic Acid
CAS No.	148257-06-1
Molecular Formula	C₁₄H₂₁NO₄
Molecular Weight	267.32 g/mol
Synonyms	1,1-Dimethylethyl (1R,2S,3S,4R)-3-Amino-2-bicyclo[2.2.1]hept-5-ene-2-carboxylate; tert-Butyl (1R,2S,3S,4R)-3-amino-2-bicyclo[2.2.1]hept-5-ene-2-carboxylate; BOC-3-exo-ABHCA; (1R,2S,3S,4R)-3-[(tert-Butoxycarbonyl)amino]bicyclo[2.2.1]hept-5-ene-2-carboxylic Acid; N-Boc-3-exo-Aminobicyclo[2.2.1]hept-5-ene-2-exo-carboxylic Acid; BOC-ABH Acid; Protected 3-Aminonorbornene-2-carboxylic Acid
EINECS	Contact for details

Quality Control

Our Boc-3-Exo-Aminobicyclo[2.2.1]Hept-5-Ene-2-Exo-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain purity. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.