Description

Piperazinone, 3-(3,3-Difluoro-2-Oxopropylidene)- (9Ci) is a specialized heterocyclic building block featuring a reactive difluoroketone moiety. This compound is of significant value in advanced organic synthesis, particularly for the development of novel pharmaceuticals and agrochemicals. It serves as a key intermediate for medicinal chemists and R&D professionals seeking to incorporate unique fluorinated scaffolds into target molecules. The CAS number for this compound is 147917-04-2.

Application

This high-value intermediate is utilized in sophisticated chemical synthesis across several industries:

• Pharmaceutical Research & Development: As a crucial building block for synthesizing novel active pharmaceutical ingredients (APIs), especially in the discovery of enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the difluorinated structure can enhance biological activity and stability.
• Fluorine Chemistry & Material Science: Acts as a precursor for creating advanced fluorinated materials, liquid crystals, or specialty polymers with tailored properties.
• Contract Research Organizations (CROs) & CDMOs: Supplied to organizations specializing in custom synthesis and process development for client projects.
• Academic Research: Employed in university and institutional labs for methodological studies in heterocyclic and fluorine chemistry.

Basic Information

Product Name	Piperazinone, 3-(3,3-Difluoro-2-Oxopropylidene)- (9Ci)
CAS No.	147917-04-2
Molecular Formula	C7H8F2N2O2
Molecular Weight	190.15 g/mol
Synonyms	3-(3,3-Difluoro-2-oxopropylidene)piperazin-2-one; 3-(3,3-Difluoro-2-oxopropylidene)piperazinone; 1,4-Diaza-2-cyclohexen-5-one, 3-(3,3-difluoro-2-oxopropylidene)-; Difluorinated Piperazinone Ketone; Reactive Difluoroketone Piperazinone Derivative
EINECS	Contact for details

Quality Control

Our production of Piperazinone, 3-(3,3-Difluoro-2-Oxopropylidene)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.