Description

4H-1-Benzopyran-8-Carboxylic Acid, 3-Methyl-4-Oxo-2-Phenyl-, 2-(1-Pipe Ridinyl)Cyclohexyl Ester, Hydrochloride, trans-(+-)- is a high-purity, complex organic compound belonging to the benzopyran class, serving as a critical advanced intermediate in pharmaceutical research and development. Its value lies in its specific stereochemistry and functional groups, which make it a valuable building block for synthesizing novel active pharmaceutical ingredients (APIs) and other fine chemicals. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality intermediates for complex synthesis pathways.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Chemical Research & Development: Used as a sophisticated starting material or intermediate in academic and industrial organic chemistry research for method development and novel compound libraries.
• Agrochemical Synthesis: Potential intermediate in the development of new generation pesticides or herbicides requiring complex chiral structures.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, dyes, and functional materials where precise molecular architecture is required.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in laboratories analyzing similar compounds.

Basic Information

Product Name	4H-1-Benzopyran-8-Carboxylic Acid, 3-Methyl-4-Oxo-2-Phenyl-, 2-(1-Pipe Ridinyl)Cyclohexyl Ester, Hydrochloride, trans-(+-)-
CAS No.	147528-38-9
Molecular Formula	C28H31NO4 · HCl
Molecular Weight	482.01 g/mol (as hydrochloride salt)
Synonyms	trans-(±)-2-(1-Piperidinyl)cyclohexyl 3-methyl-4-oxo-2-phenyl-4H-1-benzopyran-8-carboxylate hydrochloride; 3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic acid 2-(1-piperidinyl)cyclohexyl ester hydrochloride (trans, racemic); 4H-Chromene-8-carboxylic acid derivative; Benzopyran carboxylate ester hydrochloride; AChE inhibitor intermediate; (trans)-2-Piperidin-1-yl-cyclohexyl 3-methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylate hydrochloride
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced under strict quality management systems. We employ rigorous analytical protocols including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing assay, chiral purity, related substances, and residual solvents is provided with each shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere (e.g., nitrogen or argon) in a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% trans isomer
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.