Description

1-Piperazinepropanoic Acid, 1,1-Dimethylethyl Ester is a high-purity, protected piperazine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate, enabling the controlled introduction of the piperazine moiety into complex molecular architectures. Pharmaceutical and agrochemical research and development teams need it for the synthesis of active pharmaceutical ingredients (APIs), drug candidates, and other fine chemicals where precise structural control is paramount.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antimicrobial research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific piperazine-based structures.
• Peptide Mimetics & Conjugates: Serves as a spacer or functional group in the design of peptide analogs and bioconjugates.
• Ligand & Catalyst Development: Employed in the creation of specialized ligands for metal catalysis and molecular recognition applications.
• Chemical Biology Probes: Utilized in the synthesis of tool compounds and probes for studying biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes under GMP or non-GMP conditions.

Basic Information

Product Name	1-Piperazinepropanoic Acid, 1,1-Dimethylethyl Ester
CAS No.	147135-94-2
Molecular Formula	C11H22N2O2
Molecular Weight	214.31 g/mol
Synonyms	tert-Butyl 3-(piperazin-1-yl)propanoate; 3-(1-Piperazinyl)propanoic Acid tert-Butyl Ester; 1-Boc-3-(piperazin-1-yl)propanoic Acid (common misnomer); 3-Piperazin-1-yl-propionic acid tert-butyl ester; N-Boc-3-piperazin-1-yl-propionic acid; tert-Butyl 3-(1-piperazinyl)propionate; 1-(2-tert-Butoxy-2-oxoethyl)piperazine
EINECS	Contact for details

Quality Control

Our 1-Piperazinepropanoic Acid, 1,1-Dimethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates, from research to commercial scale.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.