Description

Sodium 3-[1-[(4-Chlorophenyl)Methyl]-5-(Quinolin-2-Ylmethoxy)-3-tert-Butylsulfanyl-Indol-2-Yl]-2,2-Dimethyl-Propanoate is a high-purity, non-racemic synthetic intermediate of significant importance in advanced pharmaceutical research and development. This compound is valued for its complex molecular architecture, which serves as a critical building block in the synthesis of novel therapeutic agents. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the creation of targeted drug candidates.

Application

This advanced chemical intermediate is designed for specialized applications in organic synthesis and pharmaceutical manufacturing.

• Pharmaceutical Intermediate: A key chiral precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Serves as a critical building block in the scale-up and optimization of synthetic routes for complex molecules.
• Biochemical Research: Potential use as a tool compound or probe in biochemical assays and target validation studies.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic projects.

Basic Information

Product Name	Sodium 3-[1-[(4-Chlorophenyl)Methyl]-5-(Quinolin-2-Ylmethoxy)-3-tert-Butylsulfanyl-Indol-2-Yl]-2,2-Dimethyl-Propanoate
CAS No.	147030-01-1
Molecular Formula	C34H35ClN2NaO3S
Molecular Weight	610.16 g/mol
Synonyms	Sodium 3-[1-[(4-Chlorophenyl)methyl]-5-(quinolin-2-ylmethoxy)-3-(tert-butylthio)-1H-indol-2-yl]-2,2-dimethylpropanoate; 147030-01-1; 1H-Indole-2-propanoic acid, 1-[(4-chlorophenyl)methyl]-5-[(2-quinolinylmethyl)oxy]-3-[(1,1-dimethylethyl)thio]-, sodium salt (1:1); Sodium 1-[(4-chlorobenzyl)-5-(quinolin-2-ylmethoxy)-3-(tert-butylthio)indol-2-yl]-2,2-dimethylpropionate; Tert-butylthio indole quinoline derivative sodium salt
EINECS	Contact for details

Quality Control

Our Sodium 3-[1-[(4-Chlorophenyl)Methyl]-5-(Quinolin-2-Ylmethoxy)-3-tert-Butylsulfanyl-Indol-2-Yl]-2,2-Dimethyl-Propanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and impurity profile analysis, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.