Description

(3R,4S)-3-Hydroxy-1-(4-Methoxyphenyl)-4-Phenyl-2-Azetidinone is a high-purity, stereochemically defined β-lactam compound, serving as a critical chiral building block and synthetic intermediate. Its precise stereochemistry is essential for producing enantiomerically pure pharmaceuticals and advanced fine chemicals. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of β-lactam antibiotics and other bioactive molecules requiring specific stereochemistry.
• Organic Synthesis Building Block: Used in asymmetric synthesis and medicinal chemistry research to construct complex molecular architectures.
• Agrochemical Research: Intermediate in the development of novel, stereospecific pesticides and herbicides.
• Academic & R&D: A valuable reagent for studying β-lactam chemistry, ring-opening reactions, and stereoselective transformations.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals where enantiopurity is a critical performance factor.

Basic Information

Product Name	(3R,4S)-3-Hydroxy-1-(4-Methoxyphenyl)-4-Phenyl-2-Azetidinone
CAS No.	146924-94-9
Molecular Formula	C16H15NO3
Molecular Weight	269.30 g/mol
Synonyms	(3R,4S)-3-Hydroxy-4-phenyl-1-(4-methoxyphenyl)azetidin-2-one; trans-3-Hydroxy-4-phenyl-1-(p-methoxyphenyl)-2-azetidinone; β-Lactam derivative with (3R,4S) configuration; Chiral β-lactam intermediate; 2-Azetidinone, 3-hydroxy-1-(4-methoxyphenyl)-4-phenyl-, (3R,4S)-
EINECS	Contact for details

Quality Control

Our (3R,4S)-3-Hydroxy-1-(4-Methoxyphenyl)-4-Phenyl-2-Azetidinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee identity, purity, and stereochemical integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de (diastereomeric excess)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.