Description

1,4-Piperidinedicarboxylic Acid, 4-(2-Propen-1-Yl)-, 1-(1,1-Dimethylethyl) 4-Ethyl Ester is a high-purity, functionalized piperidine derivative serving as a critical advanced intermediate in complex organic syntheses. Its value lies in the unique combination of a protected dicarboxylic acid moiety and an allyl group, offering versatile reactivity for constructing sophisticated molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is utilized to build active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its piperidine core for biological activity.
• Chemical Research & Development: A versatile scaffold in academic and industrial R&D for exploring new chemical spaces and reaction pathways.
• Ligand and Catalyst Preparation: The functional groups make it suitable for constructing complex ligands for asymmetric catalysis or metal-organic frameworks (MOFs).
• Custom Synthesis Projects: Serves as a starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis for clients.
• Fine Chemical Production: Employed in the multi-step synthesis of other high-value, low-volume specialty fine chemicals.

Basic Information

Product Name	1,4-Piperidinedicarboxylic Acid, 4-(2-Propen-1-Yl)-, 1-(1,1-Dimethylethyl) 4-Ethyl Ester
CAS No.	146603-99-8
Molecular Formula	C17H27NO4
Molecular Weight	309.40 g/mol
Synonyms	4-Allyl-1-(tert-butoxycarbonyl)piperidine-4-carboxylic acid ethyl ester; 1-Boc-4-allyl-piperidine-4-carboxylic acid ethyl ester; Ethyl 1-Boc-4-allyl-4-piperidinecarboxylate; 4-Allyl-1-N-Boc-piperidine-4-carboxylic acid ethyl ester; tert-Butyl 4-(ethoxycarbonyl)-4-(2-propen-1-yl)piperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(2-propen-1-yl)piperidine-4-carboxylic acid ethyl ester; 4-Allyl-4-(ethoxycarbonyl)piperidine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 1,4-Piperidinedicarboxylic Acid, 4-(2-Propen-1-Yl)-, 1-(1,1-Dimethylethyl) 4-Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industry segments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.