Description

Methyl-n-Dansylgalactosaminide CAS NO 146440-32-6 is a specialized fluorescently-labeled glycoside derivative, where the dansyl fluorophore is conjugated to a galactosamine moiety via a methyl linker. This compound is critical for advanced biochemical research and diagnostic development, enabling the sensitive detection and study of carbohydrate-protein interactions. It is primarily utilized by researchers and manufacturers in the fields of glycobiology, analytical chemistry, and pharmaceutical development for applications such as enzyme assays, receptor binding studies, and the development of fluorescent probes.

Application

• Glycobiology Research: As a high-sensitivity fluorescent substrate or probe for studying glycosidase and glycosyltransferase enzyme activity and kinetics.
• Diagnostic Assay Development: For the design and production of fluorescent diagnostic kits targeting specific carbohydrate-binding proteins or pathogens.
• Cell Biology & Imaging: Used in fluorescence microscopy and flow cytometry to label and track cellular receptors or glycoconjugates.
• Drug Discovery Screening: Acts as a key reagent in high-throughput screening (HTS) assays to identify inhibitors or modulators of carbohydrate-processing enzymes.
• Analytical Chemistry Standard: Serves as a reference standard in HPLC, LC-MS, or other chromatographic methods for quantifying related compounds.
• Bioconjugation & Probe Synthesis: A building block for creating more complex fluorescently-labeled glycoconjugates and molecular probes.

Basic Information

Product Name	Methyl-n-Dansylgalactosaminide
CAS No.	146440-32-6
Molecular Formula	C25H33N3O7S
Molecular Weight	519.61 g/mol
Synonyms	N-Dansylgalactosaminide, methyl derivative; Dansyl-GalNAc methyl glycoside; 5-(Dimethylamino)naphthalene-1-sulfonyl galactosaminide methyl ether; Methyl N-(5-dimethylaminonaphthalene-1-sulfonyl)-D-galactosaminide; MDG; Fluorescent GalNAc derivative
EINECS	Contact for details

Quality Control

Our Methyl-n-Dansylgalactosaminide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and spectrophotometry for fluorescence characterization. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. For long-term storage under inert atmosphere, the product is stable for extended periods. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Fluorescence Properties	Ex/Em ~335 nm / ~518 nm (solvent dependent)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.