Description

2-Piperazinecarboxylic acid, 1,1-dimethylethyl ester (9Ci) is a protected piperazine derivative, a crucial building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, particularly in the pharmaceutical sector. It is primarily needed by research chemists and process development teams in pharmaceutical, agrochemical, and fine chemical industries for constructing active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of piperazine-containing drug candidates, including potential central nervous system (CNS) agents and antimicrobials.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides where the piperazine moiety is required.
• Peptidomimetics & Bioactive Molecules: Serves as a protected amino acid analog for constructing peptide-like structures in medicinal chemistry.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal complexation studies.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic & Industrial Research: Utilized in chemical libraries and for methodological development in organic synthesis laboratories.

Basic Information

Product Name	2-Piperazinecarboxylic acid, 1,1-dimethylethyl ester (9Ci)
CAS No.	146398-94-9
Molecular Formula	C9H18N2O2
Molecular Weight	186.25 g/mol
Synonyms	tert-Butyl piperazine-2-carboxylate; 1-Boc-piperazine-2-carboxylic acid; 2-Piperazinecarboxylic acid, 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)piperazine-2-carboxylic acid; Boc-Pip-OH; Boc-Piperazine-2-carboxylic acid; 1-Boc-2-piperazinecarboxylic acid; Piperazine-2-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 2-Piperazinecarboxylic acid, 1,1-dimethylethyl ester is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent moisture absorption. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.