Description

4-(2-Amino-Ethyl)-Piperazin-2-One is a versatile heterocyclic organic compound featuring both a piperazinone core and a primary amine functional group, making it a valuable building block for complex synthesis. This bifunctional nature is critical for researchers and manufacturers developing advanced pharmaceutical intermediates and fine chemicals. It is particularly sought after by the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery and material science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules, particularly those targeting neurological and cardiovascular systems.
• Agrochemical Synthesis: Building block for creating novel active ingredients in herbicides, fungicides, and plant growth regulators.
• Ligand and Chelating Agent: Used in the preparation of ligands for catalysis and metal complexation due to its amine and carbonyl groups.
• Polymer Modification: Serves as a monomer or cross-linking agent for producing specialty polymers with enhanced properties.
• Bioconjugation Chemistry: Utilized in the development of biochemical probes and antibody-drug conjugates (ADCs).
• Research & Development: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	4-(2-Amino-Ethyl)-Piperazin-2-One
CAS No.	145625-71-4
Molecular Formula	C6H13N3O
Molecular Weight	143.19 g/mol
Synonyms	2-(2-Oxo-1-piperazinyl)ethylamine; 1-(2-Aminoethyl)piperazin-2-one; 4-(2-Aminoethyl)-2-piperazinone; 2-Piperazinone, 4-(2-aminoethyl)-; 4-(2-Aminoethyl)piperazin-2-one; AE-Pip; 2-Aminoethylpiperazinone
EINECS	Contact for details

Quality Control

Our 4-(2-Amino-Ethyl)-Piperazin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.