Description

11-Hydroxy-6,9,12-octadecatrienoic acid is a hydroxylated derivative of linolenic acid, a key fatty acid with significant biological activity. This compound is valued for its role as a biochemical intermediate and its potential in modulating inflammatory and metabolic pathways. It is primarily utilized by researchers and manufacturers in the pharmaceutical, nutraceutical, and advanced chemical synthesis sectors for developing novel therapeutic agents and bioactive compounds.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate or reference standard in the synthesis of bioactive lipid mediators and drug candidates targeting inflammation and metabolic disorders.
• Biochemical Studies: Used as a substrate or inhibitor in enzymatic assays to study lipoxygenase and cytochrome P450 pathways related to eicosanoid biosynthesis.
• Nutraceutical Formulation: Investigated for incorporation into specialized dietary supplements aimed at supporting metabolic health due to its structural similarity to other bioactive fatty acids.
• Cosmeceutical Applications: Explored for potential use in advanced skincare formulations for its anti-inflammatory and skin-barrier enhancing properties.
• Chemical Synthesis: Acts as a versatile chiral building block for the organic synthesis of complex natural products and specialized lipid analogs.
• Analytical Reference Standard: Employed as a high-purity standard in chromatography (HPLC, GC) for the quantification of hydroxylated fatty acids in various biological and industrial samples.

Basic Information

Product Name	11-Hydroxy-6,9,12-Octadecatrienoic Acid
CAS No.	145178-66-1
Molecular Formula	C18H30O3
Molecular Weight	294.43 g/mol
Synonyms	11-Hydroxy-6,9,12-octadecatrienoic acid; 11-Hydroxy-γ-linolenic acid; 11-Hydroxy-GLA; 11-Hydroxy-(6Z,9Z,12Z)-octadecatrienoic acid; 11-Hydroxyall-cis-6,9,12-octadecatrienoic acid; 11-Hydroxy-6Z,9Z,12Z-octadecatrienoic acid; (6Z,9Z,12Z)-11-Hydroxyoctadeca-6,9,12-trienoic acid
EINECS	Contact for details

Quality Control

Our 11-Hydroxy-6,9,12-octadecatrienoic acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets rigorous research and development standards. A Certificate of Analysis (COA) detailing specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. For long-term storage, keep the material in a freezer at -20°C or below. The container should be kept in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous oil or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.