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Leustroducsin B CAS NO 145142-82-1
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CAS No.:145142-82-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Leustroducsin B is a potent and selective small molecule inhibitor of the protein phosphatase PP2A, identified by its unique CAS number. This compound is a critical research tool for studying cellular signaling pathways, particularly those involving serine/threonine phosphatases and their role in cell cycle regulation and apoptosis. It is essential for researchers and developers in pharmaceutical discovery, oncology research, and biochemical assay development who require high-purity, well-characterized chemical probes.
Application
- Biochemical Research: Used as a selective inhibitor to study the function and regulation of protein phosphatase 2A (PP2A) in vitro.
- Cell Biology Studies: A key tool for investigating the role of PP2A in cell cycle control, signal transduction, and programmed cell death (apoptosis).
- Oncology & Cancer Research: Employed in target validation and pathway analysis to understand tumor suppression and oncogenic signaling networks.
- Drug Discovery Screening: Serves as a reference compound or positive control in high-throughput screening assays for phosphatase inhibitors.
- Neuroscience Research: Applied in studies exploring phosphatase involvement in neuronal function and neurodegenerative disease models.
- Academic & Institutional R&D: A fundamental reagent for universities and research institutes focused on molecular biology and pharmacology.
Basic Information
| Item | Detail |
|---|---|
| Product Name | Leustroducsin B |
| CAS No. | 145142-82-1 |
| Molecular Formula | Contact for details |
| Molecular Weight | Contact for details |
| Synonyms | Leustroducsin B; (-)-Leustroducsin B; PP2A Inhibitor, Leustroducsin B; 145142-82-1; Leustroducsin B (PP2A inhibitor); (3R,4S,5S,6R)-5-[(2S,3S,4S,5R,6R)-3,4-Dihydroxy-6-methyl-5-[(2S,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-6-methyloxane-2,3,4-triol (IUPAC) |
| EINECS | Contact for details |
Quality Control
Our Leustroducsin B is produced under strict quality management protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including purity assay and identity confirmation. Certificates of Analysis (COA) detailing specific test results are available upon request to support your regulatory and research documentation needs.
Storage
Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider keeping the product at 2-8°C. Handle the material carefully to prevent contamination.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥95% |
| Water Content | ≤5.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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