Description

((7S,9As)-Octahydro-1H-Pyrido[1,2-A]Pyrazin-7-Yl)Methanol is a high-purity, advanced pharmaceutical intermediate with a defined stereochemistry. This compound matters for its critical role as a key chiral building block in the synthesis of complex active pharmaceutical ingredients (APIs), enabling the production of targeted therapeutics. It is primarily needed by R&D scientists and process chemists in the pharmaceutical and biotechnology industries for developing new drug candidates and optimizing synthetic routes.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral synthon in the multi-step synthesis of novel drug molecules, particularly in central nervous system (CNS) and anti-infective research.
• API Synthesis: Used as a building block for constructing complex molecular architectures required for final Active Pharmaceutical Ingredients (APIs).
• Process Chemistry & Scale-Up: Employed in route scouting, process development, and optimization from laboratory to pilot plant scale.
• Asymmetric Synthesis: Leverages its defined stereocenters for the enantioselective construction of other complex molecules.
• Chemical Reference Standard: Acts as a high-purity standard for analytical method development, validation, and quality control in pharmaceutical manufacturing.
• Medicinal Chemistry Research: Utilized in structure-activity relationship (SAR) studies to explore new biological targets and therapeutic areas.

Basic Information

Product Name	((7S,9As)-Octahydro-1H-Pyrido[1,2-A]Pyrazin-7-Yl)Methanol
CAS No.	145012-50-6
Molecular Formula	C9H18N2O
Molecular Weight	170.25 g/mol
Synonyms	(7S,9aS)-Octahydro-1H-pyrido[1,2-a]pyrazin-7-ylmethanol; (7S,9aS)-Octahydro-1H-pyrido[1,2-a]pyrazine-7-methanol; (7S,9aS)-Octahydro-2H-pyrido[1,2-a]pyrazine-7-methanol; (7S,9aS)-1,2,3,4,6,7,8,9-Octahydropyrido[1,2-a]pyrazine-7-methanol; (7S,9aS)-Octahydro-1H-pyrido[1,2-a]pyrazin-7-yl)methanol; (7S,9aS)-Octahydro-2H-pyrido[1,2-a]pyrazin-7-ylmethanol; (7S,9aS)-Octahydro-1H-pyrido[1,2-a]pyrazine-7-ylmethanol
EINECS	Contact for details

Quality Control

Our ((7S,9As)-Octahydro-1H-Pyrido[1,2-A]Pyrazin-7-Yl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure it meets the exacting standards required for pharmaceutical development. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.