Description

2,5-Piperidinedicarboxylic Acid, 5-Methyl Ester, (2R,5S)-Rel- is a high-purity chiral piperidine derivative, serving as a critical building block in advanced organic synthesis. Its defined stereochemistry makes it an essential intermediate for the development of novel pharmaceuticals and bioactive compounds. This product is primarily targeted at research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require precise, high-quality chiral intermediates.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced, stereospecific pesticides and herbicides.
• Asymmetric Catalysis: Employed as a ligand precursor or a chiral auxiliary in catalytic processes to induce stereoselectivity.
• Fine Chemical Production: Serves as a foundational block for synthesizing complex, high-value specialty chemicals and flavors/fragrances.
• Academic & Industrial R&D: A valuable compound for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	2,5-Piperidinedicarboxylic Acid, 5-Methyl Ester, (2R,5S)-Rel-
CAS No.	145012-49-3
Molecular Formula	C9H15NO4
Molecular Weight	201.22 g/mol
Synonyms	(2R,5S)-rel-5-Methyl 2,5-piperidinedicarboxylate; Methyl (2R,5S)-rel-piperidine-2,5-dicarboxylate; rel-(2R,5S)-5-Methoxycarbonylpiperidine-2-carboxylic Acid; 2,5-Piperidinedicarboxylic acid, 5-methyl ester, (2R,5S)-rel-; (2R,5S)-rel-5-Carbomethoxypiperidine-2-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 2,5-Piperidinedicarboxylic Acid, 5-Methyl Ester, (2R,5S)-Rel- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and production use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.