Description

2H-Pyrido[1,2-A]Pyrazin-1(6H)-One,Hexahydro-7-(Hydroxymethyl)-,cis-(9Ci) is a high-purity, advanced pharmaceutical intermediate with a complex bicyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and other therapeutic areas. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and complex organic syntheses.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in CNS-targeted therapies.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex heterocyclic frameworks.
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up synthetic routes for API manufacturing.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Custom Synthesis: A valuable substrate for contract research and manufacturing organizations (CROs/CMOs) producing specialized compounds for clients.

Basic Information

Product Name	2H-Pyrido[1,2-A]Pyrazin-1(6H)-One,Hexahydro-7-(Hydroxymethyl)-,cis-(9Ci)
CAS No.	145011-62-7
Molecular Formula	C9H14N2O2
Molecular Weight	182.22 g/mol
Synonyms	cis-Hexahydro-7-(hydroxymethyl)-2H-pyrido[1,2-a]pyrazin-1(6H)-one; (3aS,7aR)-Hexahydro-7-(hydroxymethyl)-2H-pyrido[1,2-a]pyrazin-1(6H)-one; 7-(Hydroxymethyl)hexahydro-2H-pyrido[1,2-a]pyrazin-1(6H)-one, cis-; 145011-62-7; UNII-7B8K3F1J7Q; 7B8K3F1J7Q; SCHEMBL2184041.
EINECS	Contact for details

Quality Control

Our 2H-Pyrido[1,2-A]Pyrazin-1(6H)-One,Hexahydro-7-(Hydroxymethyl)-,cis-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Ensure the storage area is well-ventilated.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.